Lapis / Perimeter active

Most of the frontier goes unseen.

Patents, papers, grants, clinical developments, regulatory activity, and competitor programs move before the market notices. Lapis watches the field continuously and isolates what can change your roadmap.

1.6B+
records
177
jurisdictions
24 / 7
active
SYS / RESEARCH PERIMETER / GLOBAL● ACTIVE
PATENTPAPERGRANTREGULATORYCLINICALENTITY
Select a patent to enter its jurisdiction
Select empty space to return
RECORDS
0
DISMISSED
0
LOCKED
0
STATUS
INGESTING

Controlled demonstration · records are synthetic · country geometry is real

System credentials
Founders Hub
Research Partner
Toronto Network
Schulich Network
Featured · 2025
Podcast guest
Cornerstone W26 cohort

What are you not seeing that could change everything?

The danger is not one missed document. It is the movement that only becomes visible when fragmented evidence is connected.

A patent alone may look irrelevant. So may a grant, a rejected filing, a new clinical protocol, or a lab’s hiring pattern. Together, they can show an outside organization entering your claim space while you are still investing in the roadmap.

New papers published since you opened this page
0.00
Volume vs. attention
The evidence expands faster than any early team can interpret it.
Live
4M3M2M1MINTERPRETIVE CAPACITY / EARLY TEAM1996200620162024
Sources: NSF Science & Engineering Indicators · ScopusMove across the curve · 1996 → 2024
01 / The blind spot

The organization behind the evidence matters more than the document.

What goes unseen is the strategic movement across records, institutions, companies, jurisdictions, and languages. That movement can block a program, weaken differentiation, or reveal an opportunity before the market notices.

PatentsUnwatched
3.7M / yr

The filing that blocks your prosecution path was submitted 18 months ago. You'll find out in due diligence.

PapersUnwatched
3.5M / yr

The lab that's 14 months ahead of your program published in March. Nobody on your team saw it.

GrantsUnwatched
$92B / yr

The NIH just funded your competitor's next two years of research. It's public record. You didn't know.

RegulatoryUnwatched
1.2M+ / yr

A rival's filing just narrowed the approval path your program depends on. It sat in a public docket for months.

CompetitorsUnwatched
70K+

The startup that just announced in your space wasn't stealth. They were just publishing in places you weren't watching.

PreprintsUnwatched
600K+ / yr

The result that reshapes your roadmap won't be peer-reviewed for a year. It's already posted. The race started without you.

ClinicalUnwatched
Trials & results

A protocol change or early endpoint can redirect a technical program before the market understands the implication.

New entitiesUnwatched
Entrants & teams

A new company rarely appears from nowhere. Inventors, grants, hiring, and filings reveal the program while it is still forming.

Cross-borderUnwatched
Jurisdictions & languages

Relevant activity is distributed across patent offices, registries, institutions, and languages your team does not monitor every day.

02 / Consequence

The evidence was public.

No single record looked decisive. Together, they revealed a competing program moving against your roadmap.

Scroll to connect01 / 04
USPTO / PATENT FAMILY
18/421,887
NIH / GRANT AWARDED
R01 GM-148312
BIORXIV / PREPRINT POSTED
2026.03.118
HELIX / HIRING SIGNAL
TEAM +7
Program movement detected
One outside organization is entering your claim space.
Confidence
0.74
Lead time
14 months
03 / Define the perimeter

Tell the system what could change your future.

Your technology, roadmap, priorities, and scientific moat become the research perimeter. That context is what turns a global record stream into intelligence specific to your decisions.

Step 01 · Tell us your space

Pick the field you work in.

Lapis prefills your scouts with sources, ontologies, and the right watchlist for your industry.

04 / Evidence reconstruction

From global noise to one defensible signal.

The scout does not search for keywords. It reconstructs technical movement, resolves who is behind it, tests the evidence against your program, and escalates only what can change a decision.

01 / INGEST
Global feeds / live● ONLINE
1.6B+ records42 jurisdictions
48,210
INGESTED
0
DISMISSED
00
ALERTED
Scroll to drive reconstructionEvidence linked · reasoning preserved · sources cited
05 / Finding delivered

By morning, the movement is visible.

Four ordinary records become one consequential finding: who is moving, where they overlap, how confident the evidence is, and what your team should do next.

Record 04 / 04
SCOUT / FINDING
FND-2026-W21-04

Three weak records resolve into one competitor movement.

Evidence reconstructed. Strategic relevance scored against the private roadmap.

Impact
ROADMAP
Confidence
0.73
Urgency
REVIEW NOW
Recommended response

Review the claim family with counsel and test the overlap against the next prosecution milestone.

Evidence linked ↗
Synthetic demonstration · reasoning path preserved · original records linked
06 / Decision value

See earlier. Defend the moat. Move with proof.

Lapis gives an early-stage leadership team the situational awareness of a dedicated intelligence function without adding another database, inbox, or analyst workflow.

01 / Strategic effect

See the incoming block

Identify the organization, technical direction, and overlap while there is still time to respond.

THREAT / EARLYEvidence linked
02 / Strategic effect

Defend the scientific moat

Know where claims are crowding, assumptions are shifting, and your position remains differentiated.

MOAT / MAPPEDEvidence linked
03 / Strategic effect

Act with evidence

Bring impact, urgency, confidence, original sources, and a practical response into one decision surface.

ACTION / READYEvidence linked
07 / Continuous operation

Intelligence that keeps working when your team cannot.

Each scout owns a source domain. Together they learn your perimeter, read the primary evidence end to end, rank materiality, and deliver a cited brief on your schedule.

Lapis scouts indexing a team's roadmap, IP portfolio, and watchlist
Learn your program

Scouts learn what you're working on, in private.

Share your roadmap, IP portfolio, and watchlist. Scouts privately index it and learn what counts as real news for your team, and what doesn't.

Book a call ↗

The result is continuity. Your external intelligence function does not pause for travel, board meetings, diligence, or the limits of human attention.

08 / Research perimeter

YOUR WORLD, CHANGING

Distance is relevance to your program. Brightness is intensity. Dashed rings are uncertainty. Watch the quiet. Then watch it break.

LNP-7 · HEPATIC-TROPIC mRNA DELIVERY
Your therapeutics program / your program
COREADJACENTPERIPHERYHORIZON
QUIET
3 scouts active · 0 documents read

Hover a point to learn why it matters to you · click to open · the field replays on demand

09 / Intelligence terrain

The whole landscape, on one canvas.

Pan across the terrain, zoom into an active field, and open any summit or white-space basin. Elevation reflects live research and filing density.

Booting console…
Drag to pan · scroll to zoom · click a summit or basin
10 / Global coverage

Global science, watched continuously.

Patent offices, regulators, institutions, filings, and collaborations connect across the jurisdictions and organizations moving your field. Grab the globe and spin it.

Loading country boundaries · drag to rotate · select a node
11 / Evidence reconstruction

A finding your team can act on and defend.

Original records, reasoning, uncertainty, impact, and the next response sit in one brief. Every conclusion remains traceable to primary evidence.

Lapis · BriefDelivered 2d ago
High signal · Competitive IP · 2026-W21

Helix Therapeutics is 14 months ahead on hepatic-tropic LNP delivery.

From Atlas IP / Patents · Mira Literature · Felix Grants

A continuation filed last Thursday (USPTO 18/421,887) overlaps claims 3–7 of your LNP-7 prosecution path. Cross-referenced against a March bioRxiv preprint and a $1.8M NIH R01 from the same lab. This isn’t a one-off filing, it’s a coordinated program.

Convergence signal · 3 sources, one lab
Preprint · bioRxiv · 2026-03-04

“Branched ionizable lipids enable selective hepatocyte delivery of large mRNA payloads”

Schaefer Lab, TU Munich · 4 authors · 87 citations

Grant · NIH R01 · awarded 2025-09

GM-148312 · $1.8M over 4 years · same lead investigator

Mechanism: hepatic LNP delivery for mRNA therapeutics

Patent · USPTO continuation · 2026-05-15

Application 18/421,887, claims 3–7 overlap LNP-7 chemistry

Two prior-art references appear missing from prosecution

Why it matters

If granted as filed, claims 3–7 would constrain your hepatic delivery program in US and EU markets, directly affecting your Q3 prosecution plan.

Recommended next step

Review claims 3–7 against your prosecution strategy. We’ve flagged two prior-art references they may have missed, both linked in the full brief.

3 sources cited · full reasoning in appOpen full brief
1.6B+ records ingested · Lapis internal database

Patent offices. Research databases. Industry signals.

Patents, papers, and industry signals, ingested the moment they publish. The set below is a live sample; we bring new feeds and jurisdictions online every week.

USPTO
+7K/week
EPO
+2.2K/week
WIPO
+5.5K/week
KIPO
+4K/week
JPO
+6K/week
IP Australia
+550/week
CIPO
+495/week
arXiv
+6.5K/week
PubMed
+30K/week
Semantic Scholar
+50K/week
OpenAlex
+125K/week
bioRxiv
+1.2K/week
CORE
+65K/week
Europe PMC
+22K/week
Hacker News
+40K/week
Product Hunt
+300/week
TechCrunch
+200/week
Y Combinator
+12/week
Google News
+50K/week
+ many more being added
1.6B+ records ingestedInternal intelligence database · patents · papers · grants · competitors
─── Why not just use ChatGPT

ChatGPT is great if you know what to ask. The hard part is knowing what you don’t know.

Once you know about a specific patent, anyone can summarize it. Finding it in the first place, across millions of documents, in 18-month-old data, before it shows up anywhere obvious, is the job Lapis does.

Claude logoChatGPT logoPerplexity logoGrok logoGemini logo
A chatbot / search tool
Lapis logoLapis
Answers questions you already know to ask
Surfaces the patent, lab, or grant you didn't know existed
Reads what you paste in
Reads every filing and preprint in your field, end to end
Stops when you close the tab
Runs every day, on a schedule, while you're doing your job
Generic answers, hallucinated citations
Cited findings from primary sources, with reasoning
─── Intelligence, aligned

See the movement before it changes the business.

Bring one active program. Lapis will map the organizations and external activity around it, show what changed, explain why it matters to your moat, and preserve the evidence behind the next decision.